Daily capsule supplement combining Niacinamide, Turmeric Root, Ginger Root, MSM, L-Cysteine, Boswellia Serrata, Holy Basil, Rosemary Leaf, Soy Lecithin, and BioPerine — each independently studied in peer-reviewed literature for anti-inflammatory, antioxidant, or cartilage-supportive properties — formulated by Dr. Ryan Shelton NMD at Zenith Labs, manufactured in an FDA-inspected GMP-certified U.S. facility with a 180-day satisfaction guarantee
Joint N-11, a ten-ingredient joint and cartilage support capsule supplement formulated by Dr. Ryan Shelton NMD at Zenith Labs, combining Niacinamide as the primary active ingredient alongside nine botanical, mineral, and bioavailability-enhancing compounds, available in 60-day, 90-day, and 180-day supply configurations.
AURORA, Colorado, August 20, 2026 — Arthritis and related joint conditions affect an estimated 54 million U.S. adults, according to the CDC, a clinical burden that has driven the global bone and joint health supplements market to approximately $11 billion in 2023 and a projected $16 billion by 2032, according to Zion Market Research. Zenith Labs has announced the commercial launch of Joint N-11, a ten-ingredient joint and cartilage support capsule supplement formulated by Dr. Ryan Shelton, NMD, Director of Research at Zenith Labs. The formula is built around Niacinamide — a form of Vitamin B3 with a documented clinical research record in osteoarthritis management specifically in relation to cartilage maintenance and joint function in adult subjects — alongside nine botanical, amino acid, and mineral compounds each cited in peer-reviewed literature for anti-inflammatory, antioxidant, or structural support properties in joint tissue.
Joint N-11 is manufactured in an FDA-inspected, GMP-certified facility in the United States and is available at freedomfromjointpain.net. The supplement is taken as two capsules daily with water. All ten active ingredients are individually identified on the product’s Supplement Facts panel. The formula is described by the manufacturer as free from gluten, dairy, nuts, egg, and crustaceans, and free of GMOs and BPAs.
Joint N-11 Official website at freedomfromjointpain.net (affiliate link — see disclosure below)
Product Overview
This press release reports the commercial entry of Joint N-11 into the U.S. joint health supplement market. Joint N-11 is a dietary supplement developed and marketed by Zenith Labs, a dietary supplement company based in Aurora, Colorado, operating under the direction of Dr. Ryan Shelton, NMD, Director of Research. The manufacturer has structured the formula around Niacinamide as its primary active ingredient, citing its clinical research record in osteoarthritis management, and has supplemented it with nine additional botanical, amino acid, sulfur compound, and bioavailability-enhancing ingredients.
The manufacturer states that Joint N-11 is produced in an FDA-inspected, GMP-certified facility in the United States. Under 21 CFR Part 111, dietary supplement manufacturers registered with the FDA are required to comply with current Good Manufacturing Practice regulations governing production standards, ingredient testing, quality control, and product labeling. The manufacturer does not claim that Joint N-11 replicates the outcomes of any independently conducted clinical study. All scientific citations in this press release describe independent research on individual ingredient components conducted under conditions unaffiliated with Zenith Labs.
“Joint N-11 was formulated around Niacinamide because it carries one of the most specific and replicated clinical research records of any non-pharmaceutical compound studied in relation to osteoarthritis. The Kaufman clinical series in the 1950s documented Niacinamide’s relationship to joint function across hundreds of patients, and the 1996 Jonas randomized controlled pilot trial in Inflammation Research examined Niacinamide against placebo in osteoarthritis subjects in relation to joint mobility and inflammatory markers. The remaining nine ingredients — Turmeric, Ginger, MSM, Boswellia Serrata, and others — were each selected based on peer-reviewed literature examining anti-inflammatory, antioxidant, or structural support mechanisms in joint tissue. No claim is made that Joint N-11 reproduces outcomes from any cited study; that research was conducted independently under conditions unaffiliated with Zenith Labs.”
— Dr. Ryan Shelton, NMD, Director of Research, Zenith Labs
Ingredient Overview
The following section describes the ten disclosed ingredients of Joint N-11, each accompanied by a citation to independent published research on that ingredient’s studied properties. All citations describe research conducted under conditions unaffiliated with Zenith Labs. These citations do not constitute clinical evidence that this specific product produces equivalent outcomes; no such equivalence is claimed.
Niacinamide (Vitamin B3). Niacinamide is the primary active ingredient in Joint N-11. A randomized controlled pilot study published in Inflammation Research (Jonas, W.B., et al., 1996, “The effect of niacinamide on osteoarthritis: a pilot study,” doi:10.1007/BF01778470) examined Niacinamide supplementation in adult subjects with osteoarthritis in relation to joint mobility, inflammatory markers, and anti-inflammatory medication usage compared to placebo.
Turmeric Root (Curcuma longa). A clinical study published in Clinical Interventions in Aging (Kuptniratsaikul, V., et al., 2014, “Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis,” doi:10.2147/CIA.S58535) examined Curcuma domestica extract in adult subjects with knee osteoarthritis in relation to pain and functional outcomes compared to ibuprofen.
Ginger Root (Zingiber officinale). A study published in the Indian Journal of Physiological Pharmacology (Paramdeep, G., 2013, “Efficacy and tolerability of ginger in patients of osteoarthritis of knee: a randomized double blind placebo controlled study,” doi:10.1177/0967772013491828) examined ginger supplementation in adult subjects with knee osteoarthritis in relation to pain and functional outcomes.
MSM (Methylsulfonylmethane). A randomized controlled study published in BMC Complementary and Alternative Medicine (Debbi, E.M., et al., 2011, “Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study,” doi:10.1186/1472-6882-11-50) examined MSM supplementation in adult subjects with knee osteoarthritis in relation to pain, physical function, and quality of life outcomes.
L-Cysteine. A study published in Cartilage (Simsek Ozek, N., et al., 2017, “Comparison of intra-articular injection of hyaluronic acid and L-Cysteine in the treatment of knee osteoarthritis: a pilot study,” doi:10.1177/1947603516681456) examined L-Cysteine administration in adult subjects with knee osteoarthritis in relation to joint function and tissue outcomes.
Boswellia Serrata. A randomized double-blind placebo-controlled trial published in Phytomedicine (Kimmatkar, N., et al., 2003, “Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee — a randomized double blind placebo controlled trial,” doi:10.1078/094471103321648549) examined Boswellia serrata extract in adult subjects with knee osteoarthritis in relation to pain, joint mobility, and physical function outcomes.
Holy Basil (Ocimum tenuiflorum). A study published in Food Chemistry (Tohge, T., et al., 2015, “Anti-inflammatory and antioxidative activity of anthocyanins from purple basil leaves induced by selected abiotic elicitors,” doi:10.1016/j.foodchem.2014.09.072) examined Holy Basil phytonutrient content in relation to anti-inflammatory and antioxidant activity.
Rosemary Leaf (Rosmarinus officinalis). A review published in Toxicology and Industrial Health (Ghasemzadeh Rahbardar, M., & Hosseinzadeh, H., 2014, “Nutraceuticals of anti-inflammatory activity as complementary therapy for rheumatoid arthritis,” doi:10.1177/0748233714524511) examined Rosemary and related botanical antioxidant compounds in relation to anti-inflammatory activity and tissue-protective properties.
Soy Lecithin. A study published in the Nutrition Journal (Crowley, D.C., et al., 2009, “Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee,” doi:10.1186/1475-2891-8-29) examined joint lubrication-related supplementation in adult subjects in relation to joint function outcomes.
BioPerine® (Black Pepper Extract). A review published in Critical Reviews in Food Science and Nutrition (Meghwal, M., & Goswami, T.K., 2013, “Piper nigrum and piperine: an update,” doi:10.1080/10408398.2011.571799) examined piperine’s mechanism of action in enhancing nutrient bioavailability in adult subjects.
Availability and Purchasing
Joint N-11 is available through Zenith Labs’ authorized retail portal at freedomfromjointpain.net. Three supply configurations are available: a two-bottle package (60-day supply) at $59 per bottle for a total of $118 plus $9.95 shipping; a three-bottle package (90-day supply) at $49 per bottle for a total of $147 plus $9.95 shipping; and a six-bottle package (180-day supply) at $33 per bottle for a total of $198 with free U.S. shipping. Three- and six-bottle orders include two bonus digital guides: 17 Joint-Supporting Smoothies and Youthful Joints for Life. All purchases are a one-time charge with no subscription, auto-ship, or hidden fees.
Quality and Manufacturing
Joint N-11 is manufactured in an FDA-inspected, GMP-certified facility in the United States. Under 21 CFR Part 111, the manufacturer is required to comply with current Good Manufacturing Practice regulations covering production standards, ingredient testing, quality control, and accurate product labeling. All ten active ingredients are individually identified on the product’s Supplement Facts panel in the exact dosages listed on the bottle. The manufacturer states the formula is free from gluten, dairy, nuts, egg, and crustaceans, and free of GMOs and BPAs.
Usage Guidance
Joint N-11 is intended for adult use as a daily joint support dietary supplement. The recommended serving is two capsules daily with water, preferably in the morning. Individuals who are pregnant, nursing, taking prescription medications, or managing existing medical conditions should consult a qualified healthcare professional before use. Individual results may vary.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.
Affiliate Disclosure: This press release may contain affiliate links through which the publisher may receive compensation if a purchase is made. This disclosure is made in accordance with the Federal Trade Commission’s guidelines on endorsements and testimonials (16 CFR Part 255).
About Zenith Labs
Zenith Labs is a dietary supplement company based in Aurora, Colorado, operating under the direction of Dr. Ryan Shelton, NMD, Director of Research. Joint N-11 is a ten-ingredient joint and cartilage support capsule supplement combining Niacinamide, Turmeric Root, Ginger Root, MSM, L-Cysteine, Boswellia Serrata, Holy Basil, Rosemary Leaf, Soy Lecithin, and BioPerine, manufactured in an FDA-inspected, GMP-certified U.S. facility with a 180-day satisfaction guarantee.
Media Contact
Dr. Ryan Shelton, NMD
Director of Research, Zenith Labs
support@zenithlabs.com
800800 928-1184
19655 E 35th Dr, Suite 100, Aurora, CO 80011
Author: Dr. Ryan Shelton, NMD, Zenith Labs — @ZenithLabs
Company: @ZenithLabs
Distributed By: XPR Media — @XPR_Syndicate
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